The CVP5 Kit is used to detect and identify a panel of 5 genetic variants that are associated with Cardiovascular Diseases – FV Leiden (G1691A; R506Q)/ FV R2 haplotype (H1299R) / Prothrombin (PTH; Factor II) G20210A / MTHFR C677T / MTHFR A1298C

Atherosclerosis and venous thrombosis are the two major manifestations of Cardiovascular Diseases. In the past 50 years, the molecular bases of both blood coagulation and the anticoagulant pathways have been explained, and several genetic risk factors have been identified. These genetic risk factors affect the natural anticoagulant mechanisms and result in a hypercoagulable state due to an imbalance between procoagulant and anticoagulant forces. Thrombosis is a lifelong risk, and thrombotic events tend to occur when one or more of the circumstantial risk factors come into play. It is a typical multifactor disease, with the pathogenesis involving both environmental and genetic mechanisms.